Glycidyl methacrylate

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		Group I Human					Group II and II* Human									Ecotox			Fate		Physical		Mult	Non-GSLT
	GREENSCREEN®	C Carcinogenicity	M Mutagenicity/Genotoxicity	R Reproductive Toxicity	D Developmental Toxicity incl. developmental neurotoxicity	E Endocrine Activity	AT Acute Mammalian Toxicity	ST Systemic Toxicity/Organ Effects-Single Exposure	ST Systemic Toxicity/Organ Effects incl. immunotoxicity-Repeated Exposure	N Neurotoxicity-Single Exposure	N Neurotoxicity-Repeated Exposure	SnS Skin Sensitization	SnR Respiratory Sensitization	IrS Skin Irritation/Corrosivity	IrE Eye Irritation/Corrosivity	AA Acute Aquatic Toxicity	CA Chronic Aquatic Toxicity	ATB Terrestrial Ecotoxicity	P Persistence	B Bioaccumulation	Rx Reactivity	F Flammability	Mult List specifies multiple endpoints	PBT PBT (Persistence, Bioaccumulation & Toxicity)	GW Global Warming	O Ozone Depletion	Other Other lists including Restricted Substance Lists, Positive Lists, and Exempt Lists
GreenScreen® Assessment™ FAQ		Carcinogenicity: High hazard (High confidence)	Mutagenicity/Genotoxicity: Moderate hazard (High confidence)	Reproductive Toxicity: High hazard (High confidence)	Developmental Toxicity incl. developmental neurotoxicity: Low hazard (High confidence)	Endocrine Activity: data gap	Acute Mammalian Toxicity: High hazard (High confidence)	Systemic Toxicity/Organ Effects-Single Exposure: Moderate hazard (High confidence)	Systemic Toxicity/Organ Effects incl. immunotoxicity-Repeated Exposure: High hazard (High confidence)	Neurotoxicity-Single Exposure: data gap	Neurotoxicity-Repeated Exposure: data gap	Skin Sensitization: High hazard (High confidence)	Respiratory Sensitization: Moderate hazard (Low confidence)	Skin Irritation/Corrosivity: Very high hazard (High confidence)	Eye Irritation/Corrosivity: Very high hazard (High confidence)	Acute Aquatic Toxicity: High hazard (High confidence)	Chronic Aquatic Toxicity: Moderate hazard (High confidence)	-	Persistence: Low hazard (High confidence)	Bioaccumulation: Very low hazard (High confidence)	Reactivity: Low hazard (Low confidence)	Flammability: Moderate hazard (High confidence)	-	-	-	-	R
List Hazard Summary FAQ		Carcinogenicity: High hazard (High confidence)	Mutagenicity/Genotoxicity: Moderate hazard (High confidence)	Reproductive Toxicity: High hazard (High confidence)	-	-	Acute Mammalian Toxicity: High hazard (High confidence)	Systemic Toxicity/Organ Effects-Single Exposure: Moderate hazard (High confidence)	-	-	-	Skin Sensitization: High hazard (High confidence)	-	Skin Irritation/Corrosivity: Very high hazard (High confidence)	Eye Irritation/Corrosivity: Very high hazard (High confidence)	Acute Aquatic Toxicity: High hazard (Low confidence)	-	-	-	-	-	Flammability: Moderate hazard (Low confidence)	Multiple Endpoints: Very high hazard (Low confidence)	-	-	-	R
PubMed Results																		-					-				-

Hazard Lists

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Endpoint	Hazard Level	List Name	Hazard Description	Other Lists
Carcinogenicity	Carcinogenicity: High hazard (High confidence)	CA EPA - Prop 65	Carcinogen	+9
	Carcinogenicity: High hazard (High confidence)	EU - Annex VI CMRs	Carcinogen Category 1B - Presumed Carcinogen based on animal evidence
	Carcinogenicity: High hazard (High confidence)	EU - GHS (H-Statements) Annex 6 Table 3-1	H350 - May cause cancer [Carcinogenicity - Category 1A or 1B]
	Carcinogenicity: High hazard (High confidence)	EU - REACH Annex XVII CMRs	Carcinogens: Category 1B
	Carcinogenicity: High hazard (High confidence)	IARC	Group 2A - Agent is probably Carcinogenic to humans
	Carcinogenicity: High hazard (Low confidence)	GHS - Australia	H350 - May cause cancer [Carcinogenicity - Category 1A or 1B]
	Carcinogenicity: High hazard (Low confidence)	GHS - Japan	H350 - May cause cancer [Carcinogenicity - Category 1B]
	Carcinogenicity: Potential concern hazard	ChemSec - SIN List	Carcinogen
	Carcinogenicity: Potential concern hazard	EU - Manufacturer REACH hazard submissions	H350 - May cause cancer (unverified) [Carcinogenicity - Category 1A or 1B]
	Carcinogenicity: Potential concern hazard	Silent Spring - Breast Cancer Chemicals	Chemicals that increased mammary gland tumors in animal studies
Mutagenicity/Genotoxicity	Mutagenicity/Genotoxicity: Moderate hazard (High confidence)	EU - Annex VI CMRs	Mutagen - Category 2	+4
	Mutagenicity/Genotoxicity: Moderate hazard (High confidence)	EU - GHS (H-Statements) Annex 6 Table 3-1	H341 - Suspected of causing genetic defects [Germ cell mutagenicity - Category 2]
	Mutagenicity/Genotoxicity: Moderate hazard (Low confidence)	GHS - Australia	H341 - Suspected of causing genetic defects [Germ cell mutagenicity - Category 2]
	Mutagenicity/Genotoxicity: Moderate hazard (Low confidence)	GHS - Japan	H341 - Suspected of causing genetic defects [Germ cell mutagenicity - Category 2]
	Mutagenicity/Genotoxicity: Potential concern hazard	EU - Manufacturer REACH hazard submissions	H341 - Suspected of causing genetic defects (unverified) [Germ cell mutagenicity - Category 2]
Reproductive Toxicity	Reproductive Toxicity: High hazard (High confidence)	EU - GHS (H-Statements) Annex 6 Table 3-1	H360F - May damage fertility [Reproductive toxicity - Category 1A or 1B]	+2
	Reproductive Toxicity: High hazard (Low confidence)	GHS - Australia	H360F - May damage fertility [Reproductive toxicity - Category 1A or 1B]
	Reproductive Toxicity: High hazard (Low confidence)	GHS - Japan	H360 - May damage fertility or the unborn child [Toxic to reproduction - Category 1B]
Acute Mammalian Toxicity	Acute Mammalian Toxicity: High hazard (High confidence)	EU - GHS (H-Statements) Annex 6 Table 3-1	H311 - Toxic in contact with skin [Acute toxicity (dermal) - Category 3]	+14
	Acute Mammalian Toxicity: Moderate hazard (High confidence)	EU - GHS (H-Statements) Annex 6 Table 3-1	H302 - Harmful if swallowed [Acute toxicity (oral) - Category 4]
	Acute Mammalian Toxicity: Very high to high hazard (Low confidence)	Québec CSST - WHMIS 1988	Class D1A - Very toxic material causing immediate and serious toxic effects
	Acute Mammalian Toxicity: High hazard (Low confidence)	GHS - Australia	H311 - Toxic in contact with skin [Acute toxicity (dermal) - Category 3]
	Acute Mammalian Toxicity: High hazard (Low confidence)	GHS - Japan	H311 - Toxic in contact with skin [Acute Toxicity (dermal) - Category 3]
	Acute Mammalian Toxicity: Moderate hazard (Low confidence)	GHS - Australia	H302 - Harmful if swallowed [Acute toxicity (oral) - Category 4]
	Acute Mammalian Toxicity: Moderate hazard (Low confidence)	GHS - Japan	H302 - Harmful if swallowed [Acute Toxicity (oral) - Category 4]
	Acute Mammalian Toxicity: Moderate hazard (Low confidence)	GHS - New Zealand	Acute dermal toxicity category 4
	Acute Mammalian Toxicity: Moderate hazard (Low confidence)	GHS - New Zealand	Acute inhalation toxicity category 4
	Acute Mammalian Toxicity: Moderate hazard (Low confidence)	GHS - New Zealand	Acute oral toxicity category 4
	Acute Mammalian Toxicity: Potential concern hazard	EU - Manufacturer REACH hazard submissions	H301 - Toxic if swallowed (unverified) [Acute toxicity (oral) - Category 3]
	Acute Mammalian Toxicity: Potential concern hazard	EU - Manufacturer REACH hazard submissions	H302 - Harmful if swallowed (unverified) [Acute toxicity (oral) - Category 4]
	Acute Mammalian Toxicity: Potential concern hazard	EU - Manufacturer REACH hazard submissions	H311 - Toxic in contact with skin (unverified) [Acute toxicity (dermal) - Category 3]
	Acute Mammalian Toxicity: Potential concern hazard	EU - Manufacturer REACH hazard submissions	H312 - Harmful in contact with skin (unverified) [Acute toxicity (dermal) - Category 4]
	Acute Mammalian Toxicity: Potential concern hazard	EU - Manufacturer REACH hazard submissions	H332 - Harmful if inhaled (unverified) [Acute toxicity (inhalation) - Category 4]
Systemic Toxicity/Organ Effects-Single Exposure	Systemic Toxicity/Organ Effects-Single Exposure: Moderate hazard (High confidence)	EU - GHS (H-Statements) Annex 6 Table 3-1	H335 - May cause respiratory irritation [Specific target organ toxicity - single exposure; Respiratory tract irritation - Category 3]	+3
	Systemic Toxicity/Organ Effects-Single Exposure: Moderate hazard (Low confidence)	GHS - Australia	H335 - May cause respiratory irritation [Specific target organ toxicity - single exposure; Respiratory tract irritation - Category 3]
	Systemic Toxicity/Organ Effects-Single Exposure: Potential concern hazard	EU - Manufacturer REACH hazard submissions	H335 - May cause respiratory irritation (unverified) [Specific target organ toxicity - single exposure; Respiratory tract irritation - Category 3]
	Systemic Toxicity/Organ Effects-Single Exposure: Potential concern hazard	EU - Manufacturer REACH hazard submissions	H370 - Causes damage to organs (unverified) [Specific target organ toxicity - single exposure - Category 1]
Skin Sensitization	Skin Sensitization: High hazard (High confidence)	MAK	Sensitizing Substance Sh - Danger of skin sensitization	+4
	Skin Sensitization: High to moderate hazard (Low confidence)	EU - GHS (H-Statements) Annex 6 Table 3-1	H317 - May cause an allergic skin reaction [Skin sensitization - Category 1]
	Skin Sensitization: High hazard (Low confidence)	GHS - New Zealand	Skin sensitisation category 1
	Skin Sensitization: High to moderate hazard (Low confidence)	GHS - Australia	H317 - May cause an allergic skin reaction [Skin sensitization - Category 1]
	Skin Sensitization: Potential concern hazard	EU - Manufacturer REACH hazard submissions	H317 - May cause an allergic skin reaction (unverified) [Skin sensitization - Category 1]
Skin Irritation/Corrosivity	Skin Irritation/Corrosivity: Very high hazard (High confidence)	EU - GHS (H-Statements) Annex 6 Table 3-1	H314 - Causes severe skin burns and eye damage [Skin corrosion/irritation - Category 1A or 1B or 1C]	+5
	Skin Irritation/Corrosivity: Very high hazard (Low confidence)	GHS - Australia	H314 - Causes severe skin burns and eye damage [Skin corrosion/irritation - Category 1A or 1B or 1C]
	Skin Irritation/Corrosivity: Very high hazard (Low confidence)	GHS - Japan	H314 - Causes severe skin burns and eye damage [Skin corrosion / irritation - Category 1]
	Skin Irritation/Corrosivity: High hazard (Low confidence)	GHS - New Zealand	Skin irritation category 2
	Skin Irritation/Corrosivity: Potential concern hazard	EU - Manufacturer REACH hazard submissions	H314 - Causes severe skin burns and eye damage (unverified) [Skin corrosion/irritation - Category 1A or 1B or 1C]
	Skin Irritation/Corrosivity: Potential concern hazard	EU - Manufacturer REACH hazard submissions	H315 - Causes skin irritation (unverified) [Skin corrosion/irritation - Category 2]
Eye Irritation/Corrosivity	Eye Irritation/Corrosivity: Very high hazard (High confidence)	EU - GHS (H-Statements) Annex 6 Table 3-1	H318 - Causes serious eye damage [Serious eye damage/eye irritation - Category 1]	+4
	Eye Irritation/Corrosivity: Very high hazard (Low confidence)	GHS - Japan	H318 - Causes serious eye damage [Serious eye damage / eye irritation - Category 1]
	Eye Irritation/Corrosivity: High hazard (Low confidence)	GHS - New Zealand	Eye irritation category 2
	Eye Irritation/Corrosivity: Potential concern hazard	EU - Manufacturer REACH hazard submissions	H318 - Causes serious eye damage (unverified) [Serious eye damage/eye irritation - Category 1]
	Eye Irritation/Corrosivity: Potential concern hazard	EU - Manufacturer REACH hazard submissions	H319 - Causes serious eye irritation (unverified) [Serious eye damage/eye irritation - Category 2A]
Acute Aquatic Toxicity	Acute Aquatic Toxicity: High hazard (Low confidence)	GHS - Japan	H401 - Toxic to aquatic life [Hazardous to the aquatic environment (acute) - Category 2]
Flammability	Flammability: Moderate hazard (Low confidence)	GHS - Japan	H227 - Combustible liquid [Flammable liquids - Category 4]	+1
	Flammability: Moderate hazard (Low confidence)	Québec CSST - WHMIS 1988	Class B3 - Combustible liquids
Carcinogenicity, Mutagenicity/Genotoxicity Reproductive Toxicity and/or Developmental Toxicity	Carcinogenicity, Mutagenicity/Genotoxicity Reproductive Toxicity and/or Developmental Toxicity: Unspecified hazard (Low confidence)	ChemSec - SIN List	CMR - Carcinogen, Mutagen &/or Reproductive Toxicant
Reproductive and/or Developmental Toxicity	Reproductive and/or Developmental Toxicity: High hazard (Low confidence)	EU - Annex VI CMRs	Reproductive Toxicity - Category 1B	+3
	Reproductive and/or Developmental Toxicity: High hazard (Low confidence)	EU - REACH Annex XVII CMRs	Reproductive toxicants: Category 1B
	Reproductive and/or Developmental Toxicity: Potential concern hazard	ChemSec - SIN List	Reproductive and/or developmental
	Reproductive and/or Developmental Toxicity: Potential concern hazard	EU - Manufacturer REACH hazard submissions	H360 - Suspected of / May damage fertility and/or the unborn child (unverified) [Reproductive toxicity - Category 1A or 1B]
Carcinogenicity,Mutagenicity/Genotoxicity Reproductive Toxicity, Developmental Toxicity, Acute Mammalian Toxicity, or System Toxicity/Organ Effects.	Carcinogenicity,Mutagenicity/Genotoxicity Reproductive Toxicity, Developmental Toxicity, Acute Mammalian Toxicity, or System Toxicity/Organ Effects.: Unspecified hazard (Low confidence)	Québec CSST - WHMIS 1988	Class D2B - Toxic material causing other toxic effects
Systemic Toxicity/Organ Effects [Single Exposure] and/or Neurotoxicity [Single Exposure]	Systemic Toxicity/Organ Effects [Single Exposure] and/or Neurotoxicity [Single Exposure]: Very high hazard (Low confidence)	GHS - Japan	H370 - Causes damage to organs [Specific target organs/systemic toxicity following single exposure - Category 1]
Systemic Toxicity/Organ Effects [Repeated Exposure] and/or Neurotoxicity [Repeated Exposure]	Systemic Toxicity/Organ Effects [Repeated Exposure] and/or Neurotoxicity [Repeated Exposure]: High hazard (High confidence)	EU - GHS (H-Statements) Annex 6 Table 3-1	H372 - Causes damage to organs through prolonged or repeated exposure [Specific target organ toxicity - repeated exposure - Category 1]	+3
	Systemic Toxicity/Organ Effects [Repeated Exposure] and/or Neurotoxicity [Repeated Exposure]: High hazard (Low confidence)	GHS - Australia	H372 - Causes damage to organs through prolonged or repeated exposure [Specific target organ toxicity - repeated exposure - Category 1]
	Systemic Toxicity/Organ Effects [Repeated Exposure] and/or Neurotoxicity [Repeated Exposure]: High hazard (Low confidence)	GHS - Japan	H372 - Causes damage to organs through prolonged or repeated exposure [Specific target organs/systemic toxicity following repeated exposure - Category 1]
	Systemic Toxicity/Organ Effects [Repeated Exposure] and/or Neurotoxicity [Repeated Exposure]: Potential concern hazard	EU - Manufacturer REACH hazard submissions	H372 - Causes damage to organs through prolonged or repeated exposure (unverified) [Specific target organ toxicity - repeated exposure - Category 1]
Skin and/or Respiratory Sensitization	Skin and/or Respiratory Sensitization: High to moderate hazard (Low confidence)	GHS - Japan	H317 - May cause an allergic skin reaction [Skin Sensitization - Category 1A]
T & P and/or B [(Chronic Aquatic Toxicity and Persistence) or (Acute Aquatic Toxicity and Persistence and/or Bioaccumulation)]	T & P and/or B [(Chronic Aquatic Toxicity and Persistence) or (Acute Aquatic Toxicity and Persistence and/or Bioaccumulation)]: Unspecified hazard (Low confidence)	GHS - Japan	H412 - Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment (chronic) - Category 3]
Human and/or Aquatic toxicity and/or Persistence and/or Bioaccumulation	Human and/or Aquatic toxicity and/or Persistence and/or Bioaccumulation: Unspecified hazard (Low confidence)	German FEA - Substances Hazardous to Waters	Class 3 - Severe Hazard to Waters

Download Lists

Endpoint	Hazard Level	Hazard List	Hazard Description	Other Lists
Cancer: Priority level: Red (Very High concern to avoid)	High	CA EPA - Prop 65	Carcinogen	+9
	High	EU - Annex VI CMRs	Carcinogen Category 1B - Presumed Carcinogen based on animal evidence
	High	EU - GHS (H-Statements) Annex 6 Table 3-1	H350 - May cause cancer [Carcinogenicity - Category 1A or 1B]
	High	EU - REACH Annex XVII CMRs	Carcinogens: Category 1B
	High	IARC	Group 2A - Agent is probably Carcinogenic to humans
	High	GHS - Australia	H350 - May cause cancer [Carcinogenicity - Category 1A or 1B]
	High	GHS - Japan	H350 - May cause cancer [Carcinogenicity - Category 1B]
	High	ChemSec - SIN List	Carcinogen
	Potential Concern	EU - Manufacturer REACH hazard submissions	H350 - May cause cancer (unverified) [Carcinogenicity - Category 1A or 1B]
	Potential Concern	Silent Spring - Breast Cancer Chemicals	Chemicals that increased mammary gland tumors in animal studies
Reproductive: Priority level: Red (Very High concern to avoid)	High	EU - GHS (H-Statements) Annex 6 Table 3-1	H360F - May damage fertility [Reproductive toxicity - Category 1A or 1B]	+5
	High	EU - Annex VI CMRs	Reproductive Toxicity - Category 1B
	High	EU - REACH Annex XVII CMRs	Reproductive toxicants: Category 1B
	High	GHS - Australia	H360F - May damage fertility [Reproductive toxicity - Category 1A or 1B]
	High	GHS - Japan	H360 - May damage fertility or the unborn child [Toxic to reproduction - Category 1B]
	Potential Concern	EU - Manufacturer REACH hazard submissions	H360 - Suspected of / May damage fertility and/or the unborn child (unverified) [Reproductive toxicity - Category 1A or 1B]
Gene mutation: Priority level: Orange (High concern to avoid)	Medium	EU - Annex VI CMRs	Mutagen - Category 2	+4
	Medium	EU - GHS (H-Statements) Annex 6 Table 3-1	H341 - Suspected of causing genetic defects [Germ cell mutagenicity - Category 2]
	Medium	GHS - Australia	H341 - Suspected of causing genetic defects [Germ cell mutagenicity - Category 2]
	Medium	GHS - Japan	H341 - Suspected of causing genetic defects [Germ cell mutagenicity - Category 2]
	Potential Concern	EU - Manufacturer REACH hazard submissions	H341 - Suspected of causing genetic defects (unverified) [Germ cell mutagenicity - Category 2]
Mammalian: Priority level: Orange (High concern to avoid)	High	EU - GHS (H-Statements) Annex 6 Table 3-1	H311 - Toxic in contact with skin [Acute toxicity (dermal) - Category 3]	+14
	Medium	EU - GHS (H-Statements) Annex 6 Table 3-1	H302 - Harmful if swallowed [Acute toxicity (oral) - Category 4]
	High	Québec CSST - WHMIS 1988	Class D1A - Very toxic material causing immediate and serious toxic effects
	High	GHS - Australia	H311 - Toxic in contact with skin [Acute toxicity (dermal) - Category 3]
	High	GHS - Japan	H311 - Toxic in contact with skin [Acute Toxicity (dermal) - Category 3]
	Medium	GHS - Australia	H302 - Harmful if swallowed [Acute toxicity (oral) - Category 4]
	Medium	GHS - Japan	H302 - Harmful if swallowed [Acute Toxicity (oral) - Category 4]
	Medium	GHS - New Zealand	Acute dermal toxicity category 4
	Medium	GHS - New Zealand	Acute inhalation toxicity category 4
	Medium	GHS - New Zealand	Acute oral toxicity category 4
	Potential Concern	EU - Manufacturer REACH hazard submissions	H301 - Toxic if swallowed (unverified) [Acute toxicity (oral) - Category 3]
	Potential Concern	EU - Manufacturer REACH hazard submissions	H302 - Harmful if swallowed (unverified) [Acute toxicity (oral) - Category 4]
	Potential Concern	EU - Manufacturer REACH hazard submissions	H311 - Toxic in contact with skin (unverified) [Acute toxicity (dermal) - Category 3]
	Potential Concern	EU - Manufacturer REACH hazard submissions	H312 - Harmful in contact with skin (unverified) [Acute toxicity (dermal) - Category 4]
	Potential Concern	EU - Manufacturer REACH hazard submissions	H332 - Harmful if inhaled (unverified) [Acute toxicity (inhalation) - Category 4]
Eye irritation: Priority level: Orange (High concern to avoid)	Very High	EU - GHS (H-Statements) Annex 6 Table 3-1	H318 - Causes serious eye damage [Serious eye damage/eye irritation - Category 1]	+4
	Very High	GHS - Japan	H318 - Causes serious eye damage [Serious eye damage / eye irritation - Category 1]
	High	GHS - New Zealand	Eye irritation category 2
	Potential Concern	EU - Manufacturer REACH hazard submissions	H318 - Causes serious eye damage (unverified) [Serious eye damage/eye irritation - Category 1]
	Potential Concern	EU - Manufacturer REACH hazard submissions	H319 - Causes serious eye irritation (unverified) [Serious eye damage/eye irritation - Category 2A]
Skin irritation: Priority level: Orange (High concern to avoid)	Very High	EU - GHS (H-Statements) Annex 6 Table 3-1	H314 - Causes severe skin burns and eye damage [Skin corrosion/irritation - Category 1A or 1B or 1C]	+5
	Very High	GHS - Australia	H314 - Causes severe skin burns and eye damage [Skin corrosion/irritation - Category 1A or 1B or 1C]
	Very High	GHS - Japan	H314 - Causes severe skin burns and eye damage [Skin corrosion / irritation - Category 1]
	High	GHS - New Zealand	Skin irritation category 2
	Potential Concern	EU - Manufacturer REACH hazard submissions	H314 - Causes severe skin burns and eye damage (unverified) [Skin corrosion/irritation - Category 1A or 1B or 1C]
	Potential Concern	EU - Manufacturer REACH hazard submissions	H315 - Causes skin irritation (unverified) [Skin corrosion/irritation - Category 2]
Skin sensitize: Priority level: Orange (High concern to avoid)	High	MAK	Sensitizing Substance Sh - Danger of skin sensitization	+5
	High	GHS - Japan	H317 - May cause an allergic skin reaction [Skin Sensitization - Category 1A]
	Medium	EU - GHS (H-Statements) Annex 6 Table 3-1	H317 - May cause an allergic skin reaction [Skin sensitization - Category 1]
	High	GHS - New Zealand	Skin sensitisation category 1
	Medium	GHS - Australia	H317 - May cause an allergic skin reaction [Skin sensitization - Category 1]
	Potential Concern	EU - Manufacturer REACH hazard submissions	H317 - May cause an allergic skin reaction (unverified) [Skin sensitization - Category 1]
Organ toxicant: Priority level: Orange (High concern to avoid)	High	EU - GHS (H-Statements) Annex 6 Table 3-1	H372 - Causes damage to organs through prolonged or repeated exposure [Specific target organ toxicity - repeated exposure - Category 1]	+8
	Medium	EU - GHS (H-Statements) Annex 6 Table 3-1	H335 - May cause respiratory irritation [Specific target organ toxicity - single exposure; Respiratory tract irritation - Category 3]
	Very High	GHS - Japan	H370 - Causes damage to organs [Specific target organs/systemic toxicity following single exposure - Category 1]
	High	GHS - Australia	H372 - Causes damage to organs through prolonged or repeated exposure [Specific target organ toxicity - repeated exposure - Category 1]
	High	GHS - Japan	H372 - Causes damage to organs through prolonged or repeated exposure [Specific target organs/systemic toxicity following repeated exposure - Category 1]
	Medium	GHS - Australia	H335 - May cause respiratory irritation [Specific target organ toxicity - single exposure; Respiratory tract irritation - Category 3]
	Potential Concern	EU - Manufacturer REACH hazard submissions	H335 - May cause respiratory irritation (unverified) [Specific target organ toxicity - single exposure; Respiratory tract irritation - Category 3]
	Potential Concern	EU - Manufacturer REACH hazard submissions	H370 - Causes damage to organs (unverified) [Specific target organ toxicity - single exposure - Category 1]
	Potential Concern	EU - Manufacturer REACH hazard submissions	H372 - Causes damage to organs through prolonged or repeated exposure (unverified) [Specific target organ toxicity - repeated exposure - Category 1]
Acute aquatic: Priority level: Orange (High concern to avoid)	High	GHS - Japan	H401 - Toxic to aquatic life [Hazardous to the aquatic environment (acute) - Category 2]
Chron aquatic: Priority level: Yellow (Moderate concern to avoid)	Medium	GHS - Japan	H412 - Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment (chronic) - Category 3]
Flammable: Priority level: Yellow (Moderate concern to avoid)	Medium	GHS - Japan	H227 - Combustible liquid [Flammable liquids - Category 4]	+1
	Medium	Québec CSST - WHMIS 1988	Class B3 - Combustible liquids
Multiple: Priority level: Yellow (Moderate concern to avoid)	Medium	Québec CSST - WHMIS 1988	Class D2B - Toxic material causing other toxic effects	+3
	Potential Concern	ChemSec - SIN List	CMR - Carcinogen, Mutagen &/or Reproductive Toxicant
	Potential Concern	German FEA - Substances Hazardous to Waters	Class 3 - Severe Hazard to Waters
	High	ChemSec - SIN List	Reproductive and/or developmental
Restricted list: Priority level: Blue (Potential concern. Included on a Restricted Substances List for avoidance, monitoring, or careful management)	Potential Concern	Apple Regulated Substances Specification	Reportable Substances and Future Restrictions in Products	+23
	Potential Concern	Apple Regulated Substances Specification	Restricted Substances in Products
	Potential Concern	C2C Certified v4.0 Product Standard Restricted Substances List (RSL) - Effective July 1, 2022	Children's Products
	Potential Concern	C2C Certified v4.0 Product Standard Restricted Substances List (RSL) - Effective July 1, 2022	Formulated Consumer Products
	Potential Concern	C2C Certified v4.1 Product Standard Restricted Substances - Effective July 1, 2025	All Products
	Potential Concern	C2C Certified v4.1 Product Standard Restricted Substances - Effective July 1, 2025	Cosmetics and Personal Care Products
	Potential Concern	C2C Certified v5.0 Product Standard Restricted Substances - Effective March 16, 2026	Core List - Mixtures Only
	Potential Concern	C2C Certified v5.0 Product Standard Restricted Substances - Effective March 16, 2026	Restrictions Based on Hazard Endpoints and Risk (Silver)
	Potential Concern	CA SCP - Candidate Chemicals	Candidate Chemical List
	Potential Concern	CPA - Chemical Footprint CoHC v3 (effective 2024)	GreenScreen BM-1s and LT-1s
	Potential Concern	EU - Cosmetics Regulation	Annex II - Prohibited Substances
	Potential Concern	EU - PACT-RMOA Substances	Assessment of regulatory needs
	Potential Concern	EU - PACT-RMOA Substances	Data generation and assessment
	Potential Concern	EU - PACT-RMOA Substances	Regulatory risk management
	Potential Concern	Food Contact Chemicals of Concern (FCCoCL)	Food Contact Chemicals of Concern List (FCCoCL) - TIER 3
	Potential Concern	FPF Priority Substance List from FCCdb	FPF Priority Substance List from FCCdb
	Potential Concern	GreenScreen Certified Standard for Food Service Ware RSL	Food Packaging Forum Priority Substances List
	Potential Concern	GreenScreen Certified Standard for Food Service Ware RSL	Other Chemicals of Concern
	Potential Concern	GreenScreen Certified Standard for Medical Supplies & Devices Silver-Gold RSL	GreenScreen LT-1 (based on 2018 Chemical Footprint Project)
	Potential Concern	Japan - Chemical Substances Control Law	Japan - CSCL
	Potential Concern	Living Building Challenge 4.0 - Red List of Materials & Chemicals - Effective July 10, 2026	Watch List Substances Considered for Inclusion in the Living Building Challenge Red List
	Potential Concern	MDH - Chemicals of High Concern and Priority Chemicals	Chemicals of High Concern
	Potential Concern	Substances of Very High Concern (RIVM ZZS)	Substances of Very High Concern (RIVM ZZS)
	Potential Concern	TSCA Chemical Substantial Risk Notices	TSCA - Substantial Risk Notices
Exempt: Priority level: Green (Low concern for this endpoint)	Low	GB 9685 National Food Safety Standard (2016)	GB 9685 National Food Safety Standard (2016)
Known use: Priority level: Grey (Wide range of possible hazard levels)	Neutral	Australia - National Industrial Chemicals Notification and Assessments (NICNAS)	NICNAS	+3
	Potential Concern	California Safe Cosmetics Program - Reportable Ingredient List	CSCP - Any
	Neutral	Food Contact Chemicals Database (FCCdb)	Food Contact Chemicals Database Version 5.0
	Neutral	US FDA - Inventory of Food Contact Substances Listed in 21 CFR	Authorized food contact substances
Country inventory: Priority level: Grey (Wide range of possible hazard levels)	Neutral	EC - CEPA DSL	DSL-all	+7
	Neutral	Korea Existing Chemicals List	Existing Chemicals List
	Neutral	New Zealand Inventory of Chemicals	New Zealand Inventory of Chemicals (NZIoC)
	Neutral	Philippine Inventory of Chemicals	Philippine Inventory of Chemicals
	Neutral	Taiwan Existing Chemical Substance Inventory	Taiwan Existing Chemical Substance Inventory
	Neutral	The Australian Inventory of Industrial Chemicals	The Australian Inventory of Industrial Chemicals
	Neutral	The Inventory of Existing Chemical Substance in China - 2013	IECSC-2013
	Neutral	TSCA Chemical Substance Inventory (Active-Inactive)	TSCA Commercially Active

Cradle to Cradle Certified™ List Hazards

What are C2C hazards and what do these colors mean?
How to Use These Scores in a C2C Assessment

				Acute and Chronic Tox.							Acute Aquatic Tox.				Chronic Aquatic Tox.
Carcinogenicity	Mutagenicity	Reproductive Toxicity (Repro + Dev)	Endocrine Disruption	Oral Toxicity	Dermal Toxicity	Inhalative Toxicity	Oral, Dermal, and/or Inhalative Toxicity	Neurotoxicity	Skin, Eye, and Respiratory Corrosion/Irritation	Skin and Respiratory Sensitization	Acute Aquatic Toxicity (Fish)	Acute Aquatic Toxicity (Invertibrates)	Acute Aquatic Toxicity (Algae)	Acute Aquatic Toxicity (Fish, Invertibrates, and/or Algae)	Chronic Aquatic Toxicity (Fish)	Chronic Aquatic Toxicity (Invertibrates)	Chronic Aquatic Toxicity (Algae)	Chronic Aquatic Toxicity (Fish, Invertibrates, and/or Algae)	Terrestrial	Persistence	Bioaccumulation	Climatic Relevance	Organohalogen	Toxic Metal	Other (Human Health)	Multiple Endpoints
Carcinogen	Mutagen - Category 2	H360F - May damage fertility [Reproductive toxicity - Category 1A or 1B]	Not listed on any C2C or Pharos hazard lists	H302 - Harmful if swallowed [Acute toxicity (oral) - Category 4]	H311 - Toxic in contact with skin [Acute toxicity (dermal) - Category 3]	H335 - May cause respiratory irritation [Specific target organ toxicity - single exposure; Respiratory tract irritation - Category 3]	H372 - Causes damage to organs through prolonged or repeated exposure [Specific target organ toxicity - repeated exposure - Category 1]	Not listed on any C2C or Pharos hazard lists	H314 - Causes severe skin burns and eye damage [Skin corrosion/irritation - Category 1A or 1B or 1C]	H317 - May cause an allergic skin reaction [Skin sensitization - Category 1]	Not listed on any C2C or Pharos hazard lists	Not listed on any C2C or Pharos hazard lists	Not listed on any C2C or Pharos hazard lists	H401 - Toxic to aquatic life [Hazardous to the aquatic environment (acute) - Category 2]	Not listed on any C2C or Pharos hazard lists	Not listed on any C2C or Pharos hazard lists	Not listed on any C2C or Pharos hazard lists	On a hazard list that has not been rated by C2C	Not listed on any C2C or Pharos hazard lists	Not listed on any C2C or Pharos hazard lists	Not listed on any C2C or Pharos hazard lists	No Hazards Found	This chemical is not on the Pharos list of organohalogens, but we may have missed a few. Please double-check the chemical structure to confirm there are no carbon-halogen bonds.	This chemical is not on the Pharos list of toxic metals, but we may have missed a few. Please double-check the chemical structure to confirm there are no toxic metals.	H227 - Combustible liquid [Flammable liquids - Category 4]	CMR - Carcinogen, Mutagen &/or Reproductive Toxicant

Full Hazard List By Endpoint

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Endpoint	Lists
Carcinogenicity	CA EPA - Prop 65 - Carcinogen: Red EU - Annex VI CMRs - Carcinogen Category 1B - Presumed Carcinogen based on animal evidence: Red EU - GHS (H-Statements) Annex 6 Table 3-1 - H350 - May cause cancer [Carcinogenicity - Category 1A or 1B]: Red EU - REACH Annex XVII CMRs - Carcinogens: Category 1B: Red GHS - Australia - H350 - May cause cancer [Carcinogenicity - Category 1A or 1B]: Red GHS - Japan - H350 - May cause cancer [Carcinogenicity - Category 1B]: Red IARC - Group 2A - Agent is probably Carcinogenic to humans: Red Silent Spring - Breast Cancer Chemicals - Chemicals that increased mammary gland tumors in animal studies: Not rated
Mutagenicity	EU - Annex VI CMRs - Mutagen - Category 2: Red EU - GHS (H-Statements) Annex 6 Table 3-1 - H341 - Suspected of causing genetic defects [Germ cell mutagenicity - Category 2]: Red GHS - Australia - H341 - Suspected of causing genetic defects [Germ cell mutagenicity - Category 2]: Red GHS - Japan - H341 - Suspected of causing genetic defects [Germ cell mutagenicity - Category 2]: Red
Reproductive Toxicity (Repro + Dev)	EU - GHS (H-Statements) Annex 6 Table 3-1 - H360F - May damage fertility [Reproductive toxicity - Category 1A or 1B]: Red EU - REACH Annex XVII CMRs - Reproductive toxicants: Category 1B: Red GHS - Australia - H360F - May damage fertility [Reproductive toxicity - Category 1A or 1B]: Red GHS - Japan - H360 - May damage fertility or the unborn child [Toxic to reproduction - Category 1B]: Red
Endocrine Disruption	not listed
Oral Toxicity	EU - GHS (H-Statements) Annex 6 Table 3-1 - H302 - Harmful if swallowed [Acute toxicity (oral) - Category 4]: Red or Yellow GHS - Australia - H302 - Harmful if swallowed [Acute toxicity (oral) - Category 4]: Red or Yellow GHS - Japan - H302 - Harmful if swallowed [Acute Toxicity (oral) - Category 4]: Yellow
Dermal Toxicity	EU - GHS (H-Statements) Annex 6 Table 3-1 - H311 - Toxic in contact with skin [Acute toxicity (dermal) - Category 3]: Red GHS - Australia - H311 - Toxic in contact with skin [Acute toxicity (dermal) - Category 3]: Red GHS - Japan - H311 - Toxic in contact with skin [Acute Toxicity (dermal) - Category 3]: Red
Inhalative Toxicity	EU - GHS (H-Statements) Annex 6 Table 3-1 - H335 - May cause respiratory irritation [Specific target organ toxicity - single exposure; Respiratory tract irritation - Category 3]: Yellow GHS - Australia - H335 - May cause respiratory irritation [Specific target organ toxicity - single exposure; Respiratory tract irritation - Category 3]: Yellow
Oral, Dermal, and/or Inhalative Toxicity	EU - GHS (H-Statements) Annex 6 Table 3-1 - H372 - Causes damage to organs through prolonged or repeated exposure [Specific target organ toxicity - repeated exposure - Category 1]: Red GHS - Australia - H372 - Causes damage to organs through prolonged or repeated exposure [Specific target organ toxicity - repeated exposure - Category 1]: Red GHS - Japan - H370 - Causes damage to organs [Specific target organs/systemic toxicity following single exposure - Category 1]: Red GHS - Japan - H372 - Causes damage to organs through prolonged or repeated exposure [Specific target organs/systemic toxicity following repeated exposure - Category 1]: Red Québec CSST - WHMIS 1988 - Class D1A - Very toxic material causing immediate and serious toxic effects: Red GHS - New Zealand - Acute dermal toxicity category 4: Not rated GHS - New Zealand - Acute inhalation toxicity category 4: Not rated GHS - New Zealand - Acute oral toxicity category 4: Not rated
Neurotoxicity	not listed
Skin, Eye, and Respiratory Corrosion/Irritation	EU - GHS (H-Statements) Annex 6 Table 3-1 - H314 - Causes severe skin burns and eye damage [Skin corrosion/irritation - Category 1A or 1B or 1C]: Red EU - GHS (H-Statements) Annex 6 Table 3-1 - H318 - Causes serious eye damage [Serious eye damage/eye irritation - Category 1]: Red GHS - Australia - H314 - Causes severe skin burns and eye damage [Skin corrosion/irritation - Category 1A or 1B or 1C]: Red GHS - Japan - H314 - Causes severe skin burns and eye damage [Skin corrosion / irritation - Category 1]: Red GHS - Japan - H318 - Causes serious eye damage [Serious eye damage / eye irritation - Category 1]: Red GHS - New Zealand - Eye irritation category 2: Not rated GHS - New Zealand - Skin irritation category 2: Not rated
Skin and Respiratory Sensitization	EU - GHS (H-Statements) Annex 6 Table 3-1 - H317 - May cause an allergic skin reaction [Skin sensitization - Category 1]: Red GHS - Australia - H317 - May cause an allergic skin reaction [Skin sensitization - Category 1]: Red GHS - Japan - H317 - May cause an allergic skin reaction [Skin Sensitization - Category 1A]: Red MAK - Sensitizing Substance Sh - Danger of skin sensitization: Red GHS - New Zealand - Skin sensitisation category 1: Not rated
Acute Aquatic Toxicity (Fish)	not listed
Acute Aquatic Toxicity (Invertibrates)	not listed
Acute Aquatic Toxicity (Algae)	not listed
Acute Aquatic Toxicity (Fish, Invertibrates, and/or Algae)	GHS - Japan - H401 - Toxic to aquatic life [Hazardous to the aquatic environment (acute) - Category 2]: Red
Chronic Aquatic Toxicity (Fish)	not listed
Chronic Aquatic Toxicity (Invertibrates)	not listed
Chronic Aquatic Toxicity (Algae)	not listed
Chronic Aquatic Toxicity (Fish, Invertibrates, and/or Algae)	GHS - Japan - H412 - Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment (chronic) - Category 3]: Not rated
Terrestrial	not listed
Persistence	not listed
Bioaccumulation	not listed
Climatic Relevance	not listed
Organohalogen	not listed - This chemical is not on the Pharos list of organohalogens, but we may have missed a few. Please double-check the chemical structure to confirm there are no carbon-halogen bonds.
Toxic Metal	not listed - This chemical is not on the Pharos list of toxic metals, but we may have missed a few. Please double-check the chemical structure to confirm there are no toxic metals.
Other (Human Health)	GHS - Japan - H227 - Combustible liquid [Flammable liquids - Category 4]: Yellow Québec CSST - WHMIS 1988 - Class B3 - Combustible liquids: Yellow
Multiple Endpoints	ChemSec - SIN List - CMR - Carcinogen, Mutagen &/or Reproductive Toxicant: Red EU - Annex VI CMRs - Reproductive Toxicity - Category 1B: Red German FEA - Substances Hazardous to Waters - Class 3 - Severe Hazard to Waters: Red Québec CSST - WHMIS 1988 - Class D2B - Toxic material causing other toxic effects: Red