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Endocrine Activity

Ability to interfere with hormone communication between cells, which controls metabolism, development, growth, reproduction and behavior (the endocrine system).

Not currently included in GHS.

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Hazard lists affecting this endpoint

Hazards affecting Endocrine Activity
Hazard List Hazard Rating and Description GREENSCREEN® HPD C2C
EU - SVHC List
High hazard High confidence
Endocrine disrupting properties cause probable serious effects to the environment or human health - Banned unless Authorised Priority List Endocrine Disruption (Red)
EU - SVHC List
High hazard High confidence
Equivalent Concern - Candidate List: endocrine disrupting properties cause probable serious effects to the environment or human health Priority List Endocrine Disruption (Red)
EU - SVHC List
High hazard High confidence
Equivalent Concern - Prioritization List: endocrine disrupting properties cause probable serious effects to the environment or human health Priority List Endocrine Disruption (Red)
ChemSec - SIN List
High to moderate hazard Low confidence
Endocrine Disruption Priority List Endocrine Disruption (Red or Yellow)
EU - Priority Endocrine Disruptors
High to moderate hazard Low confidence
Category 1 - In vivo evidence of Endocrine Disruption Activity Priority List Endocrine Disruption (Red or Yellow)
EU - Priority Endocrine Disruptors
High to moderate hazard Low confidence
Category 2 - In vitro evidence of biological activity related to Endocrine Disruption Priority List Endocrine Disruption (Red or Yellow)
OSPAR - Priority PBTs & EDs & equivalent concern
High to moderate hazard Low confidence
Endocrine Disruptor - Chemical for Priority Action Priority List Endocrine Disruption (Red or Yellow)
OSPAR - Priority PBTs & EDs & equivalent concern
High to moderate hazard Low confidence
Endocrine Disruptor - Substance of Possible Concern Priority List Endocrine Disruption (Yellow)
TEDX - Potential Endocrine Disruptors
High to moderate hazard Low confidence
Potential Endocrine Disruptor Priority List Endocrine Disruption (Red or Yellow)
EU - Priority Endocrine Disruptors
Low hazard Low confidence
Category 3a (ED Studies available but no indication of ED effects) Endocrine Disruption (Green)
EU - Priority Endocrine Disruptors
High to low hazard Low confidence
Category 3b (Substances with no or insufficient data gathered) Endocrine Disruption (Red, Yellow, or Green)
ECHA Endocrine Disruptors
Potential concern hazard
ECHA Endocrine disruptor assessment list
Endocrine Disruptor Lists (Danish EPA)
Potential concern hazard
ED List I - Substances identified as endocrine disruptors at EU level
Endocrine Disruptor Lists (Danish EPA)
Potential concern hazard
ED List II - Substances under evaluation for endocrine disruption under an EU legislation
Endocrine Disruptor Lists (Danish EPA)
Potential concern hazard
ED List III - Substances considered, by the evaluating National Authority, to have endocrine disrupting properties
UNEP EDCs
Potential concern hazard
UNEP EDCs