Afatinib

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		Group I Human					Group II and II* Human									Ecotox			Fate		Physical		Mult	Non-GSLT
	GREENSCREEN®	C Carcinogenicity	M Mutagenicity/Genotoxicity	R Reproductive Toxicity	D Developmental Toxicity incl. developmental neurotoxicity	E Endocrine Activity	AT Acute Mammalian Toxicity	ST Systemic Toxicity/Organ Effects-Single Exposure	ST Systemic Toxicity/Organ Effects incl. immunotoxicity-Repeated Exposure	N Neurotoxicity-Single Exposure	N Neurotoxicity-Repeated Exposure	SnS Skin Sensitization	SnR Respiratory Sensitization	IrS Skin Irritation/Corrosivity	IrE Eye Irritation/Corrosivity	AA Acute Aquatic Toxicity	CA Chronic Aquatic Toxicity	ATB Terrestrial Ecotoxicity	P Persistence	B Bioaccumulation	Rx Reactivity	F Flammability	Mult List specifies multiple endpoints	PBT PBT (Persistence, Bioaccumulation & Toxicity)	GW Global Warming	O Ozone Depletion	Other Other lists including Restricted Substance Lists, Positive Lists, and Exempt Lists
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Endpoint	Hazard Level	GREENSCREEN®	List Name	Hazard Description	Other Lists
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Hazards