List of Breast Cancer Relevant Chemicals - EDCs
List of Breast Cancer Relevant Chemicals - Endocrine Disrupting Chemicals
This is a list of chemicals with identified evidence for endocrine-disrupting activity in the...
This is a list of chemicals with identified evidence for endocrine-disrupting activity in the Application of the Key Characteristics Framework to Identify Potential Breast Carcinogens Using Publicly Available in Vivo, in Vitro, and in Silico Data paper by Kay, et al.
- Higher confidence EDC (EDC+): chemicals that increased E2 or P4 steroidogenesis with low, medium, or high activity in CR are designated EDC+, reflecting the higher confidence for endocrine-related effects of these chemicals.
- Lower confidence EDC (EDC~): chemicals that increased only E2/P4 steroidogenesis in the single dose, were borderline-steroidogenic in CR, or weakly activated the ER (0.1> AUCagonist≥0.01, with or without borderline antagonism) are designated EDC∼, indicating lower confidence.