Comparison: XPS Blowing Agents

		Group I Human					Group II and II* Human									Ecotox			Fate		Physical		Mult	Non-GSLT
Chemical	GREENSCREEN®	C Carcinogenicity	M Mutagenicity/Genotoxicity	R Reproductive Toxicity	D Developmental Toxicity incl. developmental neurotoxicity	E Endocrine Activity	AT Acute Mammalian Toxicity	ST Systemic Toxicity/Organ Effects-Single Exposure	ST Systemic Toxicity/Organ Effects incl. immunotoxicity-Repeated Exposure	N Neurotoxicity-Single Exposure	N Neurotoxicity-Repeated Exposure	SnS Skin Sensitization	SnR Respiratory Sensitization	IrS Skin Irritation/Corrosivity	IrE Eye Irritation/Corrosivity	AA Acute Aquatic Toxicity	CA Chronic Aquatic Toxicity	ATB Terrestrial Ecotoxicity	P Persistence	B Bioaccumulation	Rx Reactivity	F Flammability	Mult List specifies multiple endpoints	PBT PBT (Persistence, Bioaccumulation & Toxicity)	GW Global Warming	O Ozone Depletion	Other Other lists including Restricted Substance Lists, Positive Lists, and Exempt Lists
1,1,1,2-TETRAFLUOROETHANE (HFC-134A) 811-97-2		-	-	-	Developmental Toxicity incl. developmental neurotoxicity: Moderate to low hazard Low confidence	-	Acute Mammalian Toxicity: Potential concern hazard	Systemic Toxicity/Organ Effects-Single Exposure: Moderate hazard Low confidence	-	-	-	-	-	-	-	Acute Aquatic Toxicity: Potential concern hazard	-	-	Persistence: Very high to high hazard Low confidence	-	-	-	Reproductive and/or Developmental Toxicity: Unspecified hazard Low confidence	-	Global Warming: High hazard	-	R
1,1-Difluoroethane 75-37-6		Carcinogenicity: Potential concern hazard	Mutagenicity/Genotoxicity: Potential concern hazard	-	-	-	-	Systemic Toxicity/Organ Effects-Single Exposure: Moderate hazard Low confidence	-	-	-	-	-	-	-	-	-	-	Persistence: Very high to high hazard Low confidence	-	-	Flammability: High hazard Low confidence	Reproductive and/or Developmental Toxicity: Unspecified hazard Low confidence	-	Global Warming: Moderate hazard	-	R
Isobutane 75-28-5		-	-	-	Developmental Toxicity incl. developmental neurotoxicity: High to low hazard Low confidence	-	-	Systemic Toxicity/Organ Effects-Single Exposure: Moderate hazard Low confidence	-	-	-	-	-	-	-	-	-	-	Persistence: Very high to high hazard Low confidence	-	-	Flammability: High hazard High confidence	Reproductive and/or Developmental Toxicity: Very high hazard Low confidence	-	-	-	R
Methyl chloride 74-87-3		Carcinogenicity: High hazard High confidence	Mutagenicity/Genotoxicity: Moderate hazard Low confidence	Reproductive Toxicity: High hazard High confidence	Developmental Toxicity incl. developmental neurotoxicity: High hazard High confidence	-	Acute Mammalian Toxicity: High to moderate hazard Low confidence	Systemic Toxicity/Organ Effects-Single Exposure: Moderate hazard Low confidence	Systemic Toxicity/Organ Effects incl. immunotoxicity-Repeated Exposure: Moderate hazard High confidence	-	Neurotoxicity-Repeated Exposure: Very high to moderate hazard Low confidence	-	-	Skin Irritation/Corrosivity: Potential concern hazard	-	-	-	-	Persistence: Very high to high hazard Low confidence	-	-	Flammability: High hazard High confidence	Reproductive and/or Developmental Toxicity: Very high hazard Low confidence	-	Global Warming: Potential concern hazard	Ozone Depletion: High hazard	R
Dimethyl ether 115-10-6		Carcinogenicity: Potential concern hazard	Mutagenicity/Genotoxicity: Potential concern hazard	-	Developmental Toxicity incl. developmental neurotoxicity: High to low hazard Low confidence	-	-	Systemic Toxicity/Organ Effects-Single Exposure: Moderate hazard Low confidence	-	Neurotoxicity-Single Exposure: Potential concern hazard	-	-	-	-	Eye Irritation/Corrosivity: High hazard Low confidence	-	-	-	Persistence: Very high to high hazard Low confidence	-	-	Flammability: High hazard High confidence	Reproductive and/or Developmental Toxicity: Unspecified hazard Low confidence	-	Global Warming: Potential concern hazard	-	R
Methyl formate 107-31-3		-	-	-	Developmental Toxicity incl. developmental neurotoxicity: Moderate to low hazard Low confidence	-	Acute Mammalian Toxicity: Moderate hazard High confidence	Systemic Toxicity/Organ Effects-Single Exposure: Moderate hazard High confidence	-	-	Neurotoxicity-Repeated Exposure: Very high to moderate hazard Low confidence	-	-	Skin Irritation/Corrosivity: High hazard Low confidence	Eye Irritation/Corrosivity: High hazard High confidence	-	-	-	Persistence: Very high to high hazard Low confidence	-	-	Flammability: Very high hazard High confidence	Reproductive and/or Developmental Toxicity: Very high hazard Low confidence	-	-	-	R
Pentane 109-66-0		-	-	-	Developmental Toxicity incl. developmental neurotoxicity: Moderate to low hazard Low confidence	-	Acute Mammalian Toxicity: Potential concern hazard	Systemic Toxicity/Organ Effects-Single Exposure: High hazard Low confidence	-	Neurotoxicity-Single Exposure: Moderate to low hazard Low confidence	Neurotoxicity-Repeated Exposure: Very high to low hazard Low confidence	-	-	Skin Irritation/Corrosivity: Potential concern hazard	Eye Irritation/Corrosivity: High hazard Low confidence	Acute Aquatic Toxicity: High hazard Low confidence	-	-	Persistence: Very high to high hazard Low confidence	-	-	Flammability: High hazard High confidence	Reproductive and/or Developmental Toxicity: High hazard High confidence	-	Global Warming: Moderate hazard	-	R
Water 7732-18-5		Carcinogenicity: Low hazard (High confidence)	Mutagenicity/Genotoxicity: Low hazard (High confidence)	Reproductive Toxicity: Low hazard (High confidence)	Developmental Toxicity incl. developmental neurotoxicity: Low hazard (High confidence)	Endocrine Activity: Low hazard (Low confidence)	Acute Mammalian Toxicity: Low hazard (High confidence)	Systemic Toxicity/Organ Effects-Single Exposure: Low hazard (Low confidence)	Systemic Toxicity/Organ Effects incl. immunotoxicity-Repeated Exposure: Low hazard (Low confidence)	Neurotoxicity-Single Exposure: Low hazard (Low confidence)	Neurotoxicity-Repeated Exposure: Low hazard (Low confidence)	Skin Sensitization: Low hazard (Low confidence)	Respiratory Sensitization: Low hazard (Low confidence)	Skin Irritation/Corrosivity: Low hazard (Low confidence)	Eye Irritation/Corrosivity: Low hazard (Low confidence)	Acute Aquatic Toxicity: Low hazard (High confidence)	Chronic Aquatic Toxicity: Low hazard (High confidence)	-	Persistence: High hazard (High confidence)	Bioaccumulation: Low hazard (Low confidence)	Reactivity: Low hazard (High confidence)	Flammability: Low hazard (High confidence)	-	-	-	-	R
carbon dioxide 463-79-6		-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	+
1,3,3,3-Tetrafluoropropene, (1E)- 29118-24-9		-	-	-	Developmental Toxicity incl. developmental neurotoxicity: Moderate to low hazard Low confidence	-	-	-	-	-	-	-	-	-	-	-	-	-	Persistence: Potential concern hazard	-	-	-	Reproductive and/or Developmental Toxicity: Unspecified hazard Low confidence	-	-	-	R

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